HDAC6-IN-35
HDAC6-IN-35 (compound C4 (ZINC000077541942)) is a potent and BBB-penetrated HDAC6 inhibitor with the IC50 of 4.7 μM. HDAC6-IN-35 shows cell toxicity against MDA-MB-231 with EC50 of 40.6 μM.
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- CAS. Nr.: 1394615-06-5
- Formel: C22H25ClN2O2
- Molecular Weight:384.90
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Protokoll
- Reinheit & Dokumentation
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Help & FAQs
Biologische Aktivität
Beschreibung
IC50 & Target
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HDAC6 4.7 μM (IC50) |
Chemical Information
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CAS. Nr. 1394615-06-5
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Molecular Weight 384.90
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Formel C22H25ClN2O2
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SMILES
O=C1CC2(CN1)CCN(CC2)CC3=CC=CC(OCC4=CC=CC=C4Cl)=C3
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
HDAC6-IN-35 Related Classifications
HY-163369 Related Classifications
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