HMR 1031
HMR 1031 is a very late antigen-4 (VLA4, i.e., integrin α4β1) inhibitor, with IC50 values of 0.7 nM and 0.3 nM against VLA-4/VCAM-1 and VLA-4/fibronectin, respectively. HMR 1031 blocks allergen-induced airway responses and airway inflammation in mouse and sheep models. HMR 1031 can be used in asthma-related research.
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- CAS. Nr.: 479203-71-9
- Formel: C35H41N5O6
- Molecular Weight:627.74
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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α4β1 |
Chemical Information
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CAS. Nr. 479203-71-9
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Molecular Weight 627.74
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Formel C35H41N5O6
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SMILES
[C@@H](C(N[C@@H](CC(O)=O)C1=CC=CC=C1)=O)(CC(C)C)N2C(=O)N(CC3=CC=C(NC(NC4=C(C)C=CC=C4)=O)C=C3)C(C)(C)C2=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
HMR 1031 Related Classifications
HY-136692 Related Classifications
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