JT010 (Standard)
JT010 (Standard) is the analytical standard of JT010 (HY-111132). This product is intended for research and analytical applications. JT010 is a covalent and site-selective TRPA1 agonist. JT010 can be used in myocardial infarction research.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 917562-33-5
- Formel: C16H19ClN2O3S
- Molecular Weight:354.85
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Reinheit & Dokumentation
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Help & FAQs
Product Information
Information
Anwendung
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS. Nr. 917562-33-5
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Molecular Weight 354.85
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Formel C16H19ClN2O3S
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SMILES
O=C(N(C1=NC(C2=CC=C(OC)C=C2)=CS1)CCCOC)CCl
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Takaya J, et al. A Potent and Site-Selective Agonist of TRPA1. J Am Chem Soc. 2015 Dec 23;137(50):15859-64. [Content Brief]
[2]. Szabó K, et al. TRPA1 Covalent Ligand JT010 Modifies T Lymphocyte Activation. Biomolecules. 2024 May 28;14(6):632. [Content Brief]
[3]. Matsubara M, et al. Potent Activation of Human but Not Mouse TRPA1 by JT010. Int J Mol Sci. 2022 Nov 18;23(22):14297. [Content Brief]
[4]. Virk HS, et al. TGFβ1 induces resistance of human lung myofibroblasts to cell death via down-regulation of TRPA1 channels. Br J Pharmacol. 2021 Aug;178(15):2948-2962. [Content Brief]
[5]. Singh U, et al. Investigation of the Pathomechanism of Chronic Cough Using an In Vitro Approach. Clin Exp Allergy. 2025 Jan 21. [Content Brief]
[6]. Hoebart C, Kiss A, Pilz PM, Szabo PL, Podesser BK, Fischer MJM, Heber S. TRPA1 as Target in Myocardial Infarction. Int J Mol Sci. 2023 Jan 28;24(3):2516. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
JT010 (Standard) Related Classifications
HY-111132R Related Classifications
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