2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. TRP Channel
  4. JT010

JT010 

Cat. No.: HY-111132 Purity: 99.78%
COA Handling Instructions

JT010 is a potent agonist of TRPA1 with an EC50 of 0.65 nM.

For research use only. We do not sell to patients.

JT010 Chemical Structure

JT010 Chemical Structure

CAS No. : 917562-33-5

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Solution
10 mM * 1 mL in DMSO USD 110 In-stock
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
 USD 110 In-stock
Solid
5 mg USD 100 In-stock
10 mg USD 160 In-stock
25 mg USD 320 In-stock
50 mg USD 510 In-stock
100 mg USD 820 In-stock
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Customer Review

Based on 1 publication(s) in Google Scholar

JT010 Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE JT010

View All TRP Channel Isoform Specific Products:

View All Isoforms
TRPC TRPM TRPV TRPA TRPML

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

JT010 is a potent agonist of TRPA1 with an EC50 of 0.65 nM.

IC50 & Target

EC50: 0.65 nM (TRPA1)[1]
Molecular Weight

354.85

Appearance

Solid

Formula

C16H19ClN2O3S
CAS No.
SMILES

O=C(N(C1=NC(C2=CC=C(OC)C=C2)=CS1)CCCOC)CCl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (281.81 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8181 mL 14.0905 mL 28.1809 mL
5 mM 0.5636 mL 2.8181 mL 5.6362 mL
10 mM 0.2818 mL 1.4090 mL 2.8181 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (7.05 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (7.05 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation

Purity: 99.78%

COA (252 KB) HNMR (261 KB) LCMS (97 KB)

Handling Instructions (2659 KB)
References
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JT010 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

JT010917562-33-5JT 010JT-010TRP ChannelTransient receptor potential channelsInhibitorinhibitorinhibit

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