LDHA-IN-7
Based on 1 Customer Validation
LDHA-IN-7 (compound 21) is an oral bioactive inhibitor of lactate dehydrogenase-A (LDHA) and LDHB, with the IC50s of 72 nM and 1.2 Μm, respectively.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 99.59%
- CAS. Nr.: 3043790-15-1
- Formel: C22H18F3N3O4
- Molecular Weight:445.39
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Speicherung:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Beschreibung
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MIA PaCa-2 | IC50 |
14.12 μM
Compound: 21
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Antiproliferative activity against human MIA PaCa-2 cells incubated for 48 hrs by Hoechst 33342 and SYTOX green staining based confocal imaging analysis
Antiproliferative activity against human MIA PaCa-2 cells incubated for 48 hrs by Hoechst 33342 and SYTOX green staining based confocal imaging analysis
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[PMID: 38925013] |
| PANC-1 | IC50 |
43.31 μM
Compound: 21
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Antiproliferative activity against human PANC-1 cells incubated for 48 hrs by Hoechst 33342 and SYTOX green staining based confocal imaging analysis
Antiproliferative activity against human PANC-1 cells incubated for 48 hrs by Hoechst 33342 and SYTOX green staining based confocal imaging analysis
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[PMID: 38925013] |
Chemical Information
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CAS. Nr. 3043790-15-1
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Appearance Solid
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Molecular Weight 445.39
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Formel C22H18F3N3O4
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Color White to off-white
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SMILES
O=C(O)C(C1=CC=C(C(F)(F)F)C=C1)CC(NC2=CC=C(C(C3=NC=CN3C)=O)C=C2)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 104 mg/mL (233.50 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2452 mL | 11.2261 mL | 22.4522 mL | 56.1306 mL |
| 5 mM | 0.4490 mL | 2.2452 mL | 4.4904 mL | 11.2261 mL | |
| 10 mM | 0.2245 mL | 1.1226 mL | 2.2452 mL | 5.6131 mL | |
| 15 mM | 0.1497 mL | 0.7484 mL | 1.4968 mL | 3.7420 mL | |
| 20 mM | 0.1123 mL | 0.5613 mL | 1.1226 mL | 2.8065 mL | |
| 25 mM | 0.0898 mL | 0.4490 mL | 0.8981 mL | 2.2452 mL | |
| 30 mM | 0.0748 mL | 0.3742 mL | 0.7484 mL | 1.8710 mL | |
| 40 mM | 0.0561 mL | 0.2807 mL | 0.5613 mL | 1.4033 mL | |
| 50 mM | 0.0449 mL | 0.2245 mL | 0.4490 mL | 1.1226 mL | |
| 60 mM | 0.0374 mL | 0.1871 mL | 0.3742 mL | 0.9355 mL | |
| 80 mM | 0.0281 mL | 0.1403 mL | 0.2807 mL | 0.7016 mL | |
| 100 mM | 0.0225 mL | 0.1123 mL | 0.2245 mL | 0.5613 mL |
LDHA-IN-7 Related Classifications
HY-162629 Related Classifications
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