lsocryptomerin
lsocryptomerin is a membrane-active antifungal compound that can be isolated from Selaginella tamariscina. lsocryptomerin can depolarize fungal plasma membrane. lsocryptomerin also shows anticancer and antibacterial activities.
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- CAS. Nr.: 20931-58-2
- Formel: C31H20O10
- Molecular Weight:552.48
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
lsocryptomerin suppresses lymphocyte proliferation and shows the cytotoxicity against human tumor cell lines[1].
lsocryptomerin (48 h) shows antifungal activity with MICs of both 18.11 μM against C. albicans, T. beigelii and S. cerevisiae[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 20931-58-2
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Molecular Weight 552.48
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Formel C31H20O10
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SMILES
O=C1C=C(C2=CC=C(OC3=C(C4=C(C=C3OC)OC(C5=CC=C(O)C=C5)=CC4=O)O)C=C2)OC6=C1C(O)=CC(O)=C6
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Lee J, et al. Isocryptomerin, a novel membrane-active antifungal compound from Selaginella tamariscina. Biochem Biophys Res Commun. 2009 Feb 13;379(3):676-80. [Content Brief]
[2]. Lee J, et al. Antibacterial and synergistic activity of isocryptomerin isolated from Selaginella tamariscina. J Microbiol Biotechnol. 2009 Feb;19(2):204-7. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)