m-PEG5-SH
Based on 1 Customer Validation
m-PEG5-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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- Reinheit: 98.0%
- CAS. Nr.: 524030-00-0
- Formel: C11H24O5S
- Molecular Weight:268.37
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Speicherung:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 524030-00-0
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Appearance Liquid (Density: 1.048 g/cm3)
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Molecular Weight 268.37
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Formel C11H24O5S
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Color Colorless to light yellow
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SMILES
COCCOCCOCCOCCOCCS
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Lösungsmittel & Löslichkeit
DMSO : ≥ 100 mg/mL (372.62 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (265 KB)
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SDS (624 KB)
- English - EN (624 KB)
- Français - FR (624 KB)
- Deutsch - DE (624 KB)
- Norwegian - NO (624 KB)
- Español - ES (624 KB)
- Swedish - SV (624 KB)
- Italian - IT (624 KB)
- Korean - KR (624 KB)
- Portuguese - PT (624 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.7262 mL | 18.6310 mL | 37.2620 mL | 93.1550 mL |
| 5 mM | 0.7452 mL | 3.7262 mL | 7.4524 mL | 18.6310 mL | |
| 10 mM | 0.3726 mL | 1.8631 mL | 3.7262 mL | 9.3155 mL | |
| 15 mM | 0.2484 mL | 1.2421 mL | 2.4841 mL | 6.2103 mL | |
| 20 mM | 0.1863 mL | 0.9315 mL | 1.8631 mL | 4.6577 mL | |
| 25 mM | 0.1490 mL | 0.7452 mL | 1.4905 mL | 3.7262 mL | |
| 30 mM | 0.1242 mL | 0.6210 mL | 1.2421 mL | 3.1052 mL | |
| 40 mM | 0.0932 mL | 0.4658 mL | 0.9315 mL | 2.3289 mL | |
| 50 mM | 0.0745 mL | 0.3726 mL | 0.7452 mL | 1.8631 mL | |
| 60 mM | 0.0621 mL | 0.3105 mL | 0.6210 mL | 1.5526 mL | |
| 80 mM | 0.0466 mL | 0.2329 mL | 0.4658 mL | 1.1644 mL | |
| 100 mM | 0.0373 mL | 0.1863 mL | 0.3726 mL | 0.9315 mL |
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