MAC-5576
MAC-5576 is a SARS-CoV-2 3CL protease inhibitor, with an IC50 of 81 nM. MAC-5576 also inhibits 3CLpro (IC50=0.5 μM), HAV 3Cpro (IC50=0.5 μM), and thrombin (IC50=13 μM).
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- CAS. Nr.: 219929-01-8
- Formel: C10H6ClNO2S
- Molecular Weight:239.68
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
Chemical Information
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CAS. Nr. 219929-01-8
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Molecular Weight 239.68
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Formel C10H6ClNO2S
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SMILES
O=C(C1=CC=CS1)OC2=CC(Cl)=CN=C2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Jan E Blanchard, et al. High-throughput screening identifies inhibitors of the SARS coronavirus main proteinase. Chem Biol. 2004 Oct;11(10):1445-53. [Content Brief]
[2]. Sho Iketani, et al. Lead compounds for the development of SARS-CoV-2 3CL protease inhibitors. Nat Commun. 2021 Apr 1;12(1):2016. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
MAC-5576 Related Classifications
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