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Art. -Nr.: HY-14456

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MAC13243 free base

2 Cited Publications

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P20 INHIBITORS Main Related Conditions: Bacterial infection.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 762239-61-2
Formel: C₂₀H₂₄ClN₃O₂S
Molecular Weight:405.94

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Please store the product under the recommended conditions in the Certificate of Analysis.

MAC13243 free base Chemical Structure

CAS. Nr.: 762239-61-2

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P20 INHIBITORS Main Related Conditions: Bacterial infection

Chemical Information

CAS. Nr. 762239-61-2
Molecular Weight 405.94
Formel C₂₀H₂₄ClN₃O₂S
SMILES

ClC1=CC=C(C=C1)CSC2=NCN(CN2)CCC3=CC=C(OC)C(OC)=C3
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Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (2)

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Nat Commun

Human iPSC-based Modeling of Pulmonary Fibrosis Reveals p300/CBP Inhibition Suppresses Alveolar Transitional Cell State. [Abstract]

2026 Feb 12;17(1):1214. PMID: 41680175
Sci Rep

Increasing the permeability of Escherichia coli using MAC13243. [Abstract]

2017 Dec 15;7(1):17629. PMID: 29247166

MAC13243 free base purchased from MedChemExpress. Usage Cited in: Sci Rep. 2017 Dec 15;7(1):17629. [Abstract]

E. coli MC4100 are grown in M9 media then exposed to different concentrations of MAC13234 (MIC=256 μg/mL) and NPN uptake was monitored (left panel). The increase in fluorescence is deemed to be due to increased permeability of the outer membrane, not cell lysis, since the amount of MAC13243 used does not affect cell viability (right panel).

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

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MAC13243 free base

2 Cited Publications

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MAC13243 free base purchased from MedChemExpress. Usage Cited in: Sci Rep. 2017 Dec 15;7(1):17629. [Abstract]

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E. coli MC4100 are grown in M9 media then exposed to different concentrations of MAC13234 (MIC=256 μg/mL) and NPN uptake was monitored (left panel). The increase in fluorescence is deemed to be due to increased permeability of the outer membrane, not cell lysis, since the amount of MAC13243 used does not affect cell viability (right panel).

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MAC13243 free base

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