MEK4 IN-4
MEK4 IN-4 is a MEK4 inhibitor (IC50 = 0.041 μM) that inhibits the kinase catalytic activity of MEK4 via competitive blockade of ATP binding. MEK4 IN-4 can be used to investigate cell proliferative diseases and disorders associated with MEK4 activity, including cancer.
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- CAS. Nr.: 2570386-33-1
- Formel: C14H9FN2O2
- Molecular Weight:256.23
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
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Help & FAQs
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Biologische Aktivität
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MAP2K4/MEK4 0.041 μM (IC50) |
MEK1 15 μM (IC50) |
MAP2K7/MEK7 12 μM (IC50) |
MEK4 IN-4 (compound 6ff) exhibits inhibitory activity against multiple MEK family subtypes in biochemical assays: it has an IC50 of 0.066 μM against MEK4 (p38), 0.10 μM against MEK4 (Jnk), 15 μM against MEK1, > 27 μM against MEK2, > 27 μM against MEK3, > 27 μM against MEK5, 11 μM against MEK6, and 12 μM against MEK7[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 2570386-33-1
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Molecular Weight 256.23
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Formel C14H9FN2O2
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SMILES
O=C(C1=CC=C(C2=C3C=CC(F)=CC3=NN2)C=C1)O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
MEK4 IN-4 Related Classifications
HY-183856 Related Classifications
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