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Mirzotamab

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Mirzotamab is an IgG1κ monoclonal antibody targeting to CD276/B7-H3 with anti-tumor activity. Mirzotamab conjugates with Clezutoclax (HY-137774), a BCL inhibitor to form Mirzotamab clezutoclax (HY-P99741), involving in research with taxane research in relapsed/refractory solid tumors. Mirzotamab clezutoclax (ABBV-155) is a targeted antibody drug conjugate (ADC).

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

  • Reinheit: 99.45%
  • CAS. Nr.: 2229859-11-2
  • Molecular Weight:144.86 kDa
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Mirzotamab
  • Experimental Validation Results for Mirzotamab
  • Experimental Validation Results for Mirzotamab
  • Mirzotamab Chemical Structure
    Mirzotamab Chemical Structure
CAS. Nr.: 2229859-11-2
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Mirzotamab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Finden Sie Ihren Händler vor Ort Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized CD276/B7-H3 Protein, Human can bind Mirzotamab. The EC50 for this effect is 13.63 ng/mL.

  • 1/16

    Flow cytometric analysis of 1X106 MCF-7 cells with Mirzotamab (HY-P99740, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Mirzotamab Chemical Structure
    1/16
  • Mirzotamab
  • Immobilized CD276/B7-H3 Protein, Human can bind Mirzotamab. The EC50 for this effect is 13.63 ng/mL.
  • Flow cytometric analysis of 1X106 MCF-7 cells with Mirzotamab (HY-P99740, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).