country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Art. -Nr.: HY-148022

Copy Link Print Information

NSC 330770

NSC 330770, a demethylated hydrogenated molecule, is a potent tubulin polymerization inhibitor (IC₅₀ of 2 μM). NSC 330770 elicites GTPase activity and the formation of abnormal polymers.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 82585-91-9
Formel: C₁₆H₁₇N₅O₂
Molecular Weight:311.34

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

NSC 330770 Chemical Structure

CAS. Nr.: 82585-91-9

Größe

Preis

Verfügbarkeit

Menge

Amount: USD 0.00

* Bitte wählen Sie Menge, bevor Sie Artikel hinzufügen.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

NSC 330770, a demethylated hydrogenated molecule, is a potent tubulin polymerization inhibitor (IC₅₀ of 2 μM). NSC 330770 elicites GTPase activity and the formation of abnormal polymers^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
L1210	IC₅₀	0.0047 μM Compound: 1	The compound was tested for cell growth inhibitory activity against lymphoid leukemia L1210 cell line. The compound was tested for cell growth inhibitory activity against lymphoid leukemia L1210 cell line.	[PMID: 2299631]
L1210	IC₅₀	0.0047 μM Compound: 29	Concentration required to inhibit 50% proliferation of cultured lymphoid leukemia L1210 cells was measured Concentration required to inhibit 50% proliferation of cultured lymphoid leukemia L1210 cells was measured	[PMID: 2231603]
L1210	IC₅₀	4.7 nM Compound: 1d	Inhibitory activity against lymphoid leukemia L1210 cells Inhibitory activity against lymphoid leukemia L1210 cells	[PMID: 2769680]
L1210	IC₅₀	4.7 nM Compound: 6	The compound was tested in vitro for growth of inhibitory activity against lymphoid leukemia L1210 cells The compound was tested in vitro for growth of inhibitory activity against lymphoid leukemia L1210 cells	[PMID: 2795608]
L1210	IC₅₀	4.7 nM Compound: 6q	Cytotoxicity against lymphoid leukemia L1210 cells Cytotoxicity against lymphoid leukemia L1210 cells	[PMID: 1956035]

Chemical Information

CAS. Nr. 82585-91-9
Molecular Weight 311.34
Formel C₁₆H₁₇N₅O₂
SMILES

O=C(NC1=NC(N)=C2N=C(CNC2=C1)C3=CC=CC=C3)OCC
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Barbier P, et al. Differential effects of ethyl 5-amino-2-methyl-1,2-dihydro-3-phenylpyrido[3,4-b]pyrazin-7-yl carbamate analogs modified at position C2 on tubulin polymerization, binding, and conformational changes. Biochemistry. 1995 Dec 26;34(51):16821-9. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

Angebot einholen Auf Lager

Other size

Angebot einholen