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Art. -Nr.: HY-187053

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O-Methylnotopterol

O-Methylnotopterol is a coumarin compound. O-Methylnotopterol inhibits LPS (HY-D1056)-induced nitric oxide production with an IC₅₀ value of 12.7 μM.

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CAS. Nr.: 88206-48-8
Formel: C₂₂H₂₄O₅
Molecular Weight:368.43

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

O-Methylnotopterol Chemical Structure

CAS. Nr.: 88206-48-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
- In Vitro
Chemical Information
Protokoll (1)
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

O-Methylnotopterol is a coumarin compound. O-Methylnotopterol inhibits LPS (HY-D1056)-induced nitric oxide production with an IC₅₀ value of 12.7 μM^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
RAW264.7	IC50	12.7 μM	Inhibition of LPS-induced nitric oxide production in murine macrophage RAW 264.7 cells. Inhibition of LPS-induced nitric oxide production in murine macrophage RAW 264.7 cells.	30291965

In Vitro

O-Methylnotopterol (Compound 12) (12.7 μM) potently inhibits LPS-induced nitric oxide production in RAW 264.7 cells with an IC₅₀ of 12.7 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.

Chemical Information

CAS. Nr. 88206-48-8
Molecular Weight 368.43
Formel C₂₂H₂₄O₅
SMILES

O(C/C=C(/CC(C=C(C)C)OC)\C)C=1C2=C(C=C3C1C=CO3)OC(=O)C=C2
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Protokoll

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Zheng X, et al. Nitric oxide inhibitory coumarins from the roots and rhizomes of Notopterygium incisum. Fitoterapia. 2018 Nov;131:65-72. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

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100 mg

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