PDE4-IN-18
PDE4-IN-18 (compound 1l) is a PDE4 inhibitor (IC50=1.55 μM) with anti-inflammatory activity. PDE4-IN-18 exerts anti-inflammatory effects by reducing excessive immune cell infiltration and intestinal membrane formation, as well as reducing the mRNA expression of pro-inflammatory cytokines (such as TNF-α and IL-6) in synovial tissue. PDE4-IN-18 can be used in the study of rheumatoid arthritis and psoriasis.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C24H19FN2O3S
- Molecular Weight:434.48
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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PDE4 1.55 μM (IC50) |
Chemical Information
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Molecular Weight 434.48
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Formel C24H19FN2O3S
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SMILES
O=C1C2=CC(F)=CC=C2C(CC=C)=C(C3=CC(NS(=O)(C4=CC=CC=C4)=O)=CC=C3)N1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)