Peficitinib-d3
Peficitinib-d3 (ASP015K-d3) is the deuterium labeled Peficitinib (HY-19568). Peficitinib (ASP015K) is an orally active JAK inhibitor, with IC50s of 3.9, 5.0, 0.7 and 4.8 nM for JAK1, JAK2, JAK3 and Tyk2, respectively.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C18H19D3N4O2
- Molecular Weight:329.41
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 944118-01-8
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Molecular Weight 329.41
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Formel C18H19D3N4O2
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SMILES
[2H]C1=C(C(N)=O)C(N[C@@H]2[C@]3([H])C[C@@]4([H])C[C@](C3)(O)C[C@]2([H])C4)=C5C(NC([2H])=C5[2H])=N1
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Synonyms
ASP015K-d3; JNJ-54781532-d3
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)