Platyphyllonol
Platyphyllonol (Platyphyllone) can be isolated from A. japonica. Platyphyllonol shows cytotoxic effects on MCF-7 cells with IC50 values of 46.9 μg/mL.
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- CAS. Nr.: 41137-85-3
- Formel: C19H22O4
- Molecular Weight:314.38
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Speicherung:
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Biologische Aktivität
Beschreibung
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| B16-4A5 | IC50 |
>10 μM
Compound: 14
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Antimelanogenic activity in mouse B16-4A5 cells assessed as inhibition of theophylline-induced melanin production after 72 hrs by spectrophotometry relative to control
Antimelanogenic activity in mouse B16-4A5 cells assessed as inhibition of theophylline-induced melanin production after 72 hrs by spectrophotometry relative to control
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[PMID: 23910596] |
| HSC-T6 | IC50 |
54.9 μM
Compound: 3
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Antifibrotic activity against rat HSC-T6 cells assessed as inhibition of proliferation after 48 hrs by BrdU incorporation assay
Antifibrotic activity against rat HSC-T6 cells assessed as inhibition of proliferation after 48 hrs by BrdU incorporation assay
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[PMID: 21504848] |
| RAW264.7 | IC50 |
30 μM
Compound: 28
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Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production preincubated for 1 hrs followed by LPS stimulation and measured after 24 hrs by Griess reagent based analysis
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production preincubated for 1 hrs followed by LPS stimulation and measured after 24 hrs by Griess reagent based analysis
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[PMID: 33422907] |
| RAW264.7 | IC50 |
46.37 μM
Compound: 15
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Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells after 24 hrs by Griess reaction based spectrophotometry
Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells after 24 hrs by Griess reaction based spectrophotometry
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[PMID: 21807513] |
Chemical Information
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CAS. Nr. 41137-85-3
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Molecular Weight 314.38
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Formel C19H22O4
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SMILES
OC(C=C1)=CC=C1CCC(C[C@@H](O)CCC2=CC=C(O)C=C2)=O
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Synonyms
Platyphyllone
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Platyphyllonol Related Classifications
HY-N3042 Related Classifications
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