CD82
CD82 is a tetraspanin originally identified in murine T cell hybrids and later isolated from prostate cancer as KAI1, the metastasis suppressor gene whose presence restrains dissemination of prostate, lung and several other carcinomas. Like other tetraspanins it spans the membrane four times and assembles into the tetraspanin-enriched microdomain network with integrins, E-cadherin and growth factor receptors, modulating their signaling and trafficking. CD82 expression is associated with favorable prognosis in some epithelial cancers yet with poor outcome in others, underlining its context-dependent function. It also potentiates immune cell function and is implicated in HIV and HTLV-1 entry studies.
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CD82 Recombinant Proteins (2)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formel: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
