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Art. -Nr.: HY-105083A

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Pumosetrag

1 Cited Publications

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Based on 1 publication(s) in Google Scholar

Pumosetrag is a bioavtive small molecular compound.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 153062-94-3
Formel: C₁₅H₁₇N₃O₂S
Molecular Weight:303.38

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Pumosetrag Chemical Structure

CAS. Nr.: 153062-94-3

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Publications (1)
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Bioz

Biologische Aktivität

Beschreibung

Pumosetrag is a bioavtive small molecular compound.

Alle 5-HT Receptor Isoform-spezifische Produkte anzeigen :

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	EC₅₀	5.4 nM Compound: DDP733	Partial agonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as effect on serotonin-induced response Partial agonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as effect on serotonin-induced response	[PMID: 21146988]
HEK293	EC₅₀	9.2 nM Compound: DDP733	Partial agonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as decrease in 10 uM 5-chloroindole-induced increase in intracellular calcium release Partial agonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as decrease in 10 uM 5-chloroindole-induced increase in intracellular calcium release	[PMID: 21146988]

Chemical Information

CAS. Nr. 153062-94-3
Molecular Weight 303.38
Formel C₁₅H₁₇N₃O₂S
SMILES

O=C(C1=CNC(C=CS2)=C2C1=O)N[C@@H]3C4CCN(CC4)C3
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Journal Impact Factor

Expert Opin Pharmacother

Recent advances in the pharmacological management of constipation predominant irritable bowel syndrome. [Abstract]

2020 Jan;21(1):73-84. PMID: 31724881

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Choung RS, et al. Novel partial 5HT3 agonist pumosetrag reduces acid reflux events in uninvestigated GERD patients after a standard refluxogenic meal: a randomized, double-blind, placebo-controlled pharmacodynamic study. Neurogastroenterol Motil. 2014 Jan;26(1):13-20. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Pumosetrag

1 Cited Publications

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Biologische Aktivität
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Publications (1)
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Pumosetrag

Publications Citing Use of MedChemExpress (MCE) Pumosetrag

Alle 5-HT Receptor Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Publications (1)

Reinheit & Dokumentation

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Pumosetrag Related Classifications

HY-105083A Related Classifications