Sulfathiourea
Sulfathiourea is an inhibitor of Pneumocystis carinii dihydropteroate synthetase (dihydropteroate synthetase), with an IC50 of 0.022 μM and a Ki of 16.5 nM. Sulfathiourea blocks folate biosynthesis by inhibiting the enzyme that links 7,8-dihydro-6-hydroxymethylpterin pyrophosphate with p-aminobenzoic acid to form dihydropteroate. Sulfathiourea can be used in research related to *Pneumocystis carinii* pneumonia.
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- CAS. Nr.: 515-49-1
- Formel: C7H9N3O2S2
- Molecular Weight:231.29
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
Beschreibung
In Vitro
Sulfathiourea potently inhibits recombinant *Pneumocystis carinii* dihydropteroate synthase, with an IC50 of 22 nM and a Ki of 16.5 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 515-49-1
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Molecular Weight 231.29
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Formel C7H9N3O2S2
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SMILES
O=S(=O)(NC(=S)N)C1=CC=C(N)C=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Sulfathiourea Related Classifications
HY-100010 Related Classifications
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