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Art. -Nr.: HY-N15637

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Torularhodin

Torularhodin is a carotenoid with anti-cancer activity. Torularhodin induces apopotsis of tumor cells and can be used for the study of prostate cancer.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 514-92-1
Formel: C₄₀H₅₂O₂
Molecular Weight:564.84

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (261 KB)

Torularhodin Chemical Structure

CAS. Nr.: 514-92-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vivo
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Torularhodin is a carotenoid with anti-cancer activity. Torularhodin induces apopotsis of tumor cells and can be used for the study of prostate cancer^[1].

In Vivo

Torularhodin (9-18 mg/kg; p.o; every day; for 10 weeks) inhibits the growth of prostate cancer in nude mice and suggest that such an action is associated the apoptosis of tumor cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Four to six-week-old BALB/c nude mice (male, 18-22 g) were subcutaneously injected with PC-3 cells (5 × 10⁵ cells)^[1]
Dosage:

9 mg/kg, 18 mg/kg
Administration:

p.o; every day; 2 weeks before transplantation; 7 weeks after transplantation
Result:

Lowered the mean number of tumors.
Tumor degeneration, apoptosis and necrosis presented at the end of the experiment.
Increased the mRNA expressions of caspase-3, 8 and 9 in tumor tissues.
Showed Bcl-2 expression of the control group was higher than that of the carotenoid-treated group while the expression of Bax was lower than the carotenoid-treated group.

Chemical Information

CAS. Nr. 514-92-1
Molecular Weight 564.84
Formel C₄₀H₅₂O₂
SMILES

OC(/C(C)=C/C=C/C(C)=C/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)=O
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
- Microorganisms
Rhodotorula rubra
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (261 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Du C, et al. The suppression of torulene and torularhodin treatment on the growth of PC-3 xenograft prostate tumors. Biochem Biophys Res Commun. 2016 Jan 22;469(4):1146-52. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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