Triacetonamine monohydrate
Based on 1 publication(s) in Google Scholar
Triacetonamine (2,2,6,6-Tetramethyl-4-piperidone) monohydrate is used as an intermediate for the synthesis of pharmaceutical products, pesticides and photostabilizers for polymers. Triacetonamine hydrochloride has oral activity and can induce acute liver failure (ALF) in rats.
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- Reinheit: 98.0%
- CAS. Nr.: 10581-38-1
- Formel: C9H19NO2
- Molecular Weight:173.25
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Speicherung:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Publications Citing Use of MedChemExpress (MCE) Triacetonamine monohydrate
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Biologische Aktivität
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Rats (half male and female, 6-8 weeks old, 200 ± 10 g)[2]
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Dosage:200 mg, 300 mg, 400 mg/Kg
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Administration:Gavage; daily; 2 days
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Result:Showed typical hepatoenteropathology of ALF with 300 mg/Kg/day and 400 mg/Kg/day, while the group of 400 mg/Kg/day had higher mortality.
Chemical Information
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CAS. Nr. 10581-38-1
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Appearance Solid
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Molecular Weight 173.25
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Formel C9H19NO2
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Color Colorless to light yellow
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SMILES
O=C1CC(C)(C)NC(C)(C)C1.[H]O[H]
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Synonyms
2,2,6,6-Tetramethyl-4-piperidone monohydrate
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (1)
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Journal Impact Factor
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Most Recent
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Tissue Eng Regen Med
Application of Bone Marrow Mesenchymal Stem Cells Effectively Eliminates Endotoxemia to Protect Rat from Acute Liver Failure Induced by Thioacetamide. [Abstract]2022 Apr;19(2):403-415. PMID: 35122584
Lösungsmittel & Löslichkeit
DMSO : 100 mg/mL (577.20 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (271 KB)
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SDS (480 KB)
- English - EN (480 KB)
- Français - FR (480 KB)
- Deutsch - DE (480 KB)
- Norwegian - NO (480 KB)
- Español - ES (480 KB)
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- Italian - IT (480 KB)
- Korean - KR (480 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Cao JP, et al. Triacetonamine formation in a bio-oil from fast pyrolysis of sewage sludge using acetone as the absorption solvent. Bioresour Technol. 2010;101(11):4242-4245. [Content Brief]
[2]. Cao JP, et al. Triacetonamine formation in a bio-oil from fast pyrolysis of sewage sludge using acetone as the absorption solvent. Bioresour Technol. 2010 Jun;101(11):4242-5. [Content Brief]
[3]. Ting Jiang, et al. Application of Bone Marrow Mesenchymal Stem Cells Effectively Eliminates Endotoxemia to Protect Rat from Acute Liver Failure Induced by Thioacetamide. Tissue Eng Regen Med. 2022 Apr;19(2):403-415. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.7720 mL | 28.8600 mL | 57.7201 mL | 144.3001 mL |
| 5 mM | 1.1544 mL | 5.7720 mL | 11.5440 mL | 28.8600 mL | |
| 10 mM | 0.5772 mL | 2.8860 mL | 5.7720 mL | 14.4300 mL | |
| 15 mM | 0.3848 mL | 1.9240 mL | 3.8480 mL | 9.6200 mL | |
| 20 mM | 0.2886 mL | 1.4430 mL | 2.8860 mL | 7.2150 mL | |
| 25 mM | 0.2309 mL | 1.1544 mL | 2.3088 mL | 5.7720 mL | |
| 30 mM | 0.1924 mL | 0.9620 mL | 1.9240 mL | 4.8100 mL | |
| 40 mM | 0.1443 mL | 0.7215 mL | 1.4430 mL | 3.6075 mL | |
| 50 mM | 0.1154 mL | 0.5772 mL | 1.1544 mL | 2.8860 mL | |
| 60 mM | 0.0962 mL | 0.4810 mL | 0.9620 mL | 2.4050 mL | |
| 80 mM | 0.0722 mL | 0.3608 mL | 0.7215 mL | 1.8038 mL | |
| 100 mM | 0.0577 mL | 0.2886 mL | 0.5772 mL | 1.4430 mL |
Triacetonamine monohydrate Related Classifications
HY-N1131B Related Classifications
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