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Vensobafusp alfa

(Synonyms: KP-104)
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Vensobafusp alfa (KP-104) is a fusion protein composed of an IgG4 monoclonal antibody directed against terminal complement protein C5 fused to the complement factor H 1-5 domain (FH1-5). Vensobafusp alfa shows anti-inflammatory and immunomodulatory activities. The isotype control for Vensobafusp alfa can refer to Human IgG4 (S228P) kappa, Isotype Control (HY-P99003)..

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  • Reinheit: 97%
  • CAS. Nr.: 2724922-85-2
  • Molecular Weight:216.45 kDa
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Vensobafusp alfa
  • Experimental Validation Results for Vensobafusp alfa
  • Experimental Validation Results for Vensobafusp alfa
  • Vensobafusp alfa Chemical Structure
    Vensobafusp alfa Chemical Structure
CAS. Nr.: 2724922-85-2
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Assay Types
  • 1/16

    IgG4-kappa-protein

  • 1/16

    Loaded Vensobafusp alfa on ProA biosensor, can bind HY-P700862 complement C5 Protein, Human (HEK293, His) with an affinity constant of 9.905E-09 M as determined in BLI assay.

  • 1/16

    Flow cytometric analysis of 1X106 HepG2 cells labeling complement protein C5 with Vensobafusp alfa (HY-P991067, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa Isotype Control (HY-P99003, blue) was used as the isotype control.

  • Vensobafusp alfa Chemical Structure
    1/16
  • Vensobafusp alfa
  • Loaded Vensobafusp alfa on ProA biosensor, can bind HY-P700862 complement C5 Protein, Human (HEK293, His) with an affinity constant of 9.905E-09 M as determined in BLI assay.
  • Flow cytometric analysis of 1X106 HepG2 cells labeling complement protein C5 with Vensobafusp alfa (HY-P991067, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa Isotype Control (HY-P99003, blue) was used as the isotype control.
  • IgG4-kappa-protein