14-Hydroxytetradecanoic acid
Based on 1 Customer Validation
14-Hydroxytetradecanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: ≥97.0%
- CAS No.: 17278-74-9
- Formula: C14H28O3
- Molecular Weight:244.38
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
All PROTAC Linkers Isoforms
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Biological Activity
PROTACs contain two different ligands connected by a linker; one is a ligand for an E122 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 17278-74-9
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Appearance Solid
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Molecular Weight 244.38
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Formula C14H28O3
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SMILES
O=C(O)CCCCCCCCCCCCCO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
DMSO : ≥ 100 mg/mL (409.20 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (237 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.0920 mL | 20.4599 mL | 40.9199 mL | 102.2997 mL |
| 5 mM | 0.8184 mL | 4.0920 mL | 8.1840 mL | 20.4599 mL | |
| 10 mM | 0.4092 mL | 2.0460 mL | 4.0920 mL | 10.2300 mL | |
| 15 mM | 0.2728 mL | 1.3640 mL | 2.7280 mL | 6.8200 mL | |
| 20 mM | 0.2046 mL | 1.0230 mL | 2.0460 mL | 5.1150 mL | |
| 25 mM | 0.1637 mL | 0.8184 mL | 1.6368 mL | 4.0920 mL | |
| 30 mM | 0.1364 mL | 0.6820 mL | 1.3640 mL | 3.4100 mL | |
| 40 mM | 0.1023 mL | 0.5115 mL | 1.0230 mL | 2.5575 mL | |
| 50 mM | 0.0818 mL | 0.4092 mL | 0.8184 mL | 2.0460 mL | |
| 60 mM | 0.0682 mL | 0.3410 mL | 0.6820 mL | 1.7050 mL | |
| 80 mM | 0.0511 mL | 0.2557 mL | 0.5115 mL | 1.2787 mL | |
| 100 mM | 0.0409 mL | 0.2046 mL | 0.4092 mL | 1.0230 mL |