HSP Inducer

Indoxacarb ((S)-DPX-JW062) is an orally active Insecticide, Voltage-dependent sodium channel blocker, and Nicotinic acetylcholine receptor modulator. Indoxacarb induces HSP70, modulates hepatic IGF-I/IGF-II, induces oxidative stress/ROS, inhibits oxidative phosphorylation, and triggers Autophagy/Apoptosis. Indoxacarb impairs neurological function and impedes nerve excitation. Indoxacarb has been widely used for the control of agricultural and forestry pests, showing significant control efficacy against Homoptera, Coleoptera, and especially Lepidoptera insects.

Teprenone Impurity 5 (5Z-GGA) is the cis-isomer of Teprenone (HY-B0779). Teprenone Impurity 5 has inhibitory activity on the proliferation of human ovarian cancer cells Caov-3, and can block the invasion process of cancer cells. Teprenone Impurity 5 can induce the expression of heat shock protein 70 (HSP70) and thioredoxin (Trx). Teprenone Impurity 5 can be used for the research of ovarian cancer.

TRC051384 hydrochloride is a potent inducer of heat shock protein 70 (HSP70). TRC051384 hydrochloride exhibits protective effects against neuronal trauma via inhibition of necroptosis. TRC051384 hydrochloride can be used for the research of ischemic stroke.

TRC051384 (Standard) is the analytical standard of TRC051384 (HY-101712). This product is intended for research and analytical applications. TRC051384 is a potent inducer of heat shock protein 70 (HSP70). TRC051384 exhibits protective effects against neuronal trauma via inhibition of necroptosis. TRC051384 can be used for the research of ischemic stroke.