2. Cell Cycle/DNA Damage Metabolic Enzyme/Protease
  3. HSP
  4. TRC051384 hydrochloride

TRC051384 hydrochloride is a potent inducer of heat shock protein 70 (HSP70). TRC051384 hydrochloride exhibits protective effects against neuronal trauma via inhibition of necroptosis. TRC051384 hydrochloride can be used for the research of ischemic stroke.

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CAS No. : 1333327-56-2

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TRC051384 hydrochloride Related Antibodies

Top Publications Citing Use of Products

    TRC051384 hydrochloride purchased from MedChemExpress. Usage Cited in: Commun Biol. 2024 Jul 17;7(1):872.  [Abstract]

    The heat shock protein inducer TRC051384 (10 μM). ACTB was used as an endogenous reference gene.

    TRC051384 hydrochloride purchased from MedChemExpress. Usage Cited in: Commun Biol. 2024 Jul 17;7(1):872.  [Abstract]

    HEK293TAU cells were treated with TRC051384 (10 μM), and the samples were collected for western blotting.

    TRC051384 hydrochloride purchased from MedChemExpress. Usage Cited in: Clin Transl Med. 2023 Mar;13(3):e1229.  [Abstract]

    Apoptosis rates (%) were determined in Jurkat cells treated with 6 μM V8 and 15 μM ML346 or 10 μM TRC051384 (pretreated for 1 h) compared with control via flow cytometry labelling with Annexin V/PI.

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    Description

    TRC051384 hydrochloride is a potent inducer of heat shock protein 70 (HSP70). TRC051384 hydrochloride exhibits protective effects against neuronal trauma via inhibition of necroptosis. TRC051384 hydrochloride can be used for the research of ischemic stroke[1][2].

    Molecular Weight

    502.01

    Formula

    C25H32ClN5O4
    CAS No.
    SMILES

    O=C(NCCN1CCOCC1)NC2=CC=C(C=C2)C(/C=C/C3=NC(N4CCOCC4)=CC=C3)=O.Cl
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.
    Purity & Documentation
    References
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    TRC051384 hydrochloride Related Classifications

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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    TRC0513841333327-56-2TRC 051384TRC-051384HSPHeat shock proteinsneuronal traumanecroptosisischemic strokeInhibitorinhibitorinhibit

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