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Cat. No.: HY-P1729

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M-2420

M-2420 is a fluorogenic substrate containing β-secretase site of the Swedish mutation of amyloid precursor protein (APP).

For research use only. We do not sell to patients.

CAS No.: 310427-95-3
Formula: C₇₀H₉₁N₁₅O₂₇
Molecular Weight:1574.56

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

M-2420 Chemical Structure

CAS No.: 310427-95-3

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

M-2420 is a fluorogenic substrate containing β-secretase site of the Swedish mutation of amyloid precursor protein (APP)^[1].

Chemical Information

CAS No. 310427-95-3
Molecular Weight 1574.56
Formula C₇₀H₉₁N₁₅O₂₇
Sequence

{MCA}-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys{DNP}-NH2
Sequence Shortening

{MCA}-SEVNLDAEF-Lys{DNP}-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (257 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Mancini F, et al. Development of a liquid chromatographic system with fluorescent detection for beta-secretase immobilized enzyme reactor on-line enzymatic studies. J Pharm Biomed Anal. 2010 Jul 8;52(3):355-61. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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