Pranazepide
Based on 1 Customer Validation
Pranazepide (FR120480) is a selective cholecystokinin-1 receptor (CCK1-R) antagonist with an IC50 of 0.67 nM against CCK1-R. Pranazepide is applicable for the research of pancreatic diseases.
For research use only. We do not sell to patients.
- Purity: 99.81%
- CAS No.: 150408-73-4
- Formula: C26H19FN4O2
- Molecular Weight:438.45
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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CCKAR 0.67 nM (IC50) |
CCKBR 310 nM (IC50) |
Pranazepide exhibits subnanomolar affinity for CCK1-R (IC50 = 0.67 nM) and is 463-fold selective for CCK1-R over CCK2-R[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 150408-73-4
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Appearance Solid
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Molecular Weight 438.45
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Formula C26H19FN4O2
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Color White to off-white
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SMILES
O=C1N2C3=C(CC2)C=CC=C3C(C4=C(C=CC=C4)F)=N[C@@H]1NC(C5=CC6=C(C=CC=C6)N5)=O
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Synonyms
FR120480
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 125 mg/mL (285.10 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2808 mL | 11.4038 mL | 22.8076 mL | 57.0190 mL |
| 5 mM | 0.4562 mL | 2.2808 mL | 4.5615 mL | 11.4038 mL | |
| 10 mM | 0.2281 mL | 1.1404 mL | 2.2808 mL | 5.7019 mL | |
| 15 mM | 0.1521 mL | 0.7603 mL | 1.5205 mL | 3.8013 mL | |
| 20 mM | 0.1140 mL | 0.5702 mL | 1.1404 mL | 2.8510 mL | |
| 25 mM | 0.0912 mL | 0.4562 mL | 0.9123 mL | 2.2808 mL | |
| 30 mM | 0.0760 mL | 0.3801 mL | 0.7603 mL | 1.9006 mL | |
| 40 mM | 0.0570 mL | 0.2851 mL | 0.5702 mL | 1.4255 mL | |
| 50 mM | 0.0456 mL | 0.2281 mL | 0.4562 mL | 1.1404 mL | |
| 60 mM | 0.0380 mL | 0.1901 mL | 0.3801 mL | 0.9503 mL | |
| 80 mM | 0.0285 mL | 0.1425 mL | 0.2851 mL | 0.7127 mL | |
| 100 mM | 0.0228 mL | 0.1140 mL | 0.2281 mL | 0.5702 mL |
Pranazepide Related Classifications
HY-105257 Related Classifications
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