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Cat. No.: HY-123019

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RA-263

RA-263, a 2-nitroimidazole nucleoside, is an effective radiosensitizer.

For research use only. We do not sell to patients.

CAS No.: 82205-95-6
Formula: C₉H₁₁N₃O₅
Molecular Weight:241.20

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

RA-263 Chemical Structure

CAS No.: 82205-95-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

RA-263, a 2-nitroimidazole nucleoside, is an effective radiosensitizer^[1]^[2].

In Vivo

RA-263 is eliminated from plasma by a rapid alpha phase and a slower beta phase with T_1/2 of 36 and 72 min, respectively^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 82205-95-6
Molecular Weight 241.20
Formula C₉H₁₁N₃O₅
SMILES

OC1C(CO)OC(N2C=CN=C2[N+]([O-])=O)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. K C Agrawal, et al. Radiosensitization, pharmacokinetics, and toxicity of a 2-nitroimidazole nucleoside (RA-263). Radiat Res. 1986 Feb;105(2):227-39. [Content Brief]

[2]. K C Agrawal, et al. A new potent radiosensitizer: 1-(2',3'-dideoxy-alpha-D-erythro-hex-2'-enopyranosyl)-2-nitroimidazole (RA-263). Int J Radiat Oncol Biol Phys. 1982 Mar-Apr;8(3-4):403-7. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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