SC-58272
SC-58272 is a potent and selective dipeptide N-myristoyltransferase (Nmt) inhibitor with an IC50 of 56 nM for C. albicans (strain B311) Nmt. SC-58272 shows 250-fold selective for the fungal enzyme compared to human enzyme.
For research use only. We do not sell to patients.
- CAS No.: 164931-25-3
- Formula: C33H52N6O4
- Molecular Weight:596.80
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
SC-58272 shows IC50 values of 56 nM and 14100 nM for E. coli-derived human and C. albicans (strain B311) Nmts (HNmt and CaNmt, respectively)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 164931-25-3
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Molecular Weight 596.80
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Formula C33H52N6O4
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SMILES
O=C(NCCC1CCCCC1)[C@H](CCCCN)NC([C@H](CO)NC(CC2=CC=C(C=C2)CCCCN3C(C)=NC=C3)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)