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Teclistamab

(Synonyms: JNJ-7957; JNJ-64007957; Tecvayli)
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Based on 1 Customer Validation

Teclistamab is a human bispecific antibody to BCMA and CD3 that recognizes BCMA on target cells and CD3 on T cells and induces T cell-mediated cytotoxicity leading to T cell activation and subsequent target cell lysis. Teclistamab can be used in studies of diseases related to multiple myeloma (MM).

For research use only. We do not sell to patients.

  • Purity: 99.87%
  • CAS No.: 2119595-80-9
  • Molecular Weight:143.64 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Teclistamab
  • Experimental Validation Results for Teclistamab
  • Experimental Validation Results for Teclistamab
  • Experimental Validation Results for Teclistamab
  • Teclistamab Chemical Structure
    Teclistamab Chemical Structure
CAS No.: 2119595-80-9
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Teclistamab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG4 lambda

  • 1/16

    Immobilized Human CD3 epsilon/CD3e Protein (ECD, His Tag) can bind Teclistamab. The EC50 for this effect is 1.56 ng/mL.

  • 1/16

    Immobilized Human BCMA Protein (ECD, His Tag) can bind Teclistamab. The EC50 for this effect is 0.18 ng/mL.

  • 1/16

    Flow Cytometry analysis of K562 cells labelling BCMA (red) with Teclistamab (HY-P99392). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 lambda (HY-P99987, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Teclistamab Chemical Structure
    1/16
  • Teclistamab
  • Immobilized Human CD3 epsilon/CD3e Protein (ECD, His Tag) can bind Teclistamab. The EC50 for this effect is 1.56 ng/mL.
  • Immobilized Human BCMA Protein (ECD, His Tag) can bind Teclistamab. The EC50 for this effect is 0.18 ng/mL.
  • Flow Cytometry analysis of K562 cells labelling BCMA (red) with Teclistamab (HY-P99392). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 lambda (HY-P99987, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).