501A054
501A054 is an autophagy activator. 501A054 induces autophagy-dependent cell death via autophagy activation. 501A054 can be used in studies on autophagy regulation such as cervical cancer.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 3080980-06-6
- Formule: C27H35N3O2
- Masse moléculaire:433.59
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
Activité biologique
501A054 (Compound 3o) (4 h) potently activates autophagy in HeLa cells stably expressing eGFP-LC3, with an EC50 of 2.3 μM[1].
501A054 (16-32 μM; 4-24 h) induces autophagy-dependent perinuclear vacuole formation in eGFP-LC3 HeLa cells after treatment with 16 μM for 4 h[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Cell Line:eGFP-LC3 HeLa cells, ATG9A KO HeLa cells
-
Concentration:16 μM (eGFP-LC3 HeLa cells); 32 μM (ATG9A KO HeLa cells)
-
Incubation Time:4 h (eGFP-LC3 HeLa cells); 24 h (ATG9A KO HeLa cells)
-
Result:Induced perinuclear vacuole formation in eGFP-LC3 HeLa cells at 16 μM after 4 h.
Showed no vacuole formation in ATG9A KO HeLa cells at 32 μM after 24 h.
Chemical Information
-
CAS No. 3080980-06-6
-
Masse moléculaire 433.59
-
Formule C27H35N3O2
-
SMILES
OCC1CN(CCC2=CC=CC=C2)CC31CCN(CC4=CNC5=C4C=C(OC)C=C5)CC3
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
501A054 Related Classifications
HY-181724 Related Classifications
Powered by Bioz