Boc-C1-PEG2-C4-Cl
Based on 1 Customer Validation
Boc-C1-PEG2-C4-Cl (PROTAC Linker 1) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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- Pureté: 99.81%
- CAS No.: 1835705-53-7
- Formule: C14H27ClO4
- Masse moléculaire:294.81
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Stockage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
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PEGs |
Alkyl/ether |
PROTAC technology employs small molecules that recruit target proteins for ubiquitination and removal by the proteasome. The synthesis of PROTAC compounds that mediate the degradation of c-ABL and BCR-ABL by recruiting either Cereblon or Von Hippel Lindau E3 ligases is reported. Boc-C1-PEG2-C4-Cl is designated as 6-2-2[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1835705-53-7
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Appearance Liquid (Density: 1.026±0.06 g/cm3)
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Masse moléculaire 294.81
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Formule C14H27ClO4
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Color Colorless to light yellow
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SMILES
O=C(OC(C)(C)C)COCCOCCCCCCCl
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Synonyms
PROTAC Linker 1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
DMSO : ≥ 50 mg/mL (169.60 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (266 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.3920 mL | 16.9601 mL | 33.9202 mL | 84.8004 mL |
| 5 mM | 0.6784 mL | 3.3920 mL | 6.7840 mL | 16.9601 mL | |
| 10 mM | 0.3392 mL | 1.6960 mL | 3.3920 mL | 8.4800 mL | |
| 15 mM | 0.2261 mL | 1.1307 mL | 2.2613 mL | 5.6534 mL | |
| 20 mM | 0.1696 mL | 0.8480 mL | 1.6960 mL | 4.2400 mL | |
| 25 mM | 0.1357 mL | 0.6784 mL | 1.3568 mL | 3.3920 mL | |
| 30 mM | 0.1131 mL | 0.5653 mL | 1.1307 mL | 2.8267 mL | |
| 40 mM | 0.0848 mL | 0.4240 mL | 0.8480 mL | 2.1200 mL | |
| 50 mM | 0.0678 mL | 0.3392 mL | 0.6784 mL | 1.6960 mL | |
| 60 mM | 0.0565 mL | 0.2827 mL | 0.5653 mL | 1.4133 mL | |
| 80 mM | 0.0424 mL | 0.2120 mL | 0.4240 mL | 1.0600 mL | |
| 100 mM | 0.0339 mL | 0.1696 mL | 0.3392 mL | 0.8480 mL |
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