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Cat. No.: HY-101707

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UK51656

UK51656 is a calcium antagonist with IC₅₀ of 4 nM.

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CAS No.: 88150-59-8
Formule: C₂₂H₂₈ClN₃O₆
Masse moléculaire:465.93

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

UK51656 Chemical Structure

CAS No.: 88150-59-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vivo
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

UK51656 is a calcium antagonist with IC₅₀ of 4 nM.

IC₅₀ & Target

IC50: 4 nM (calcium)^[1]

Voir tous les produits spécifiques à Isoform Calcium Channel :

In Vivo

UK51656 has an elimination half-life of 4.7 h, which is consistent with its duration of action in the anesthetized dog. The effect of UK51656 on coronary vascular resistance, has markedly long durations, being over 5 h^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 88150-59-8
Masse moléculaire 465.93
Formule C₂₂H₂₈ClN₃O₆
SMILES

O=C(C(C(C(C=CC=C1)=C1Cl)C(C(OC)=O)=C(C)N2)=C2COCCNCC(N)=O)OCC
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. D Alker, et al. Long-acting dihydropyridine calcium antagonists. 4. Synthesis and structure-activity relationships for a series of basic and nonbasic derivatives of 2-[(2-aminoethoxy)methyl]-1,4-dihydropyridine calcium antagonists. J Med Chem. 1990 Feb;33 [Content Brief]

[2]. Alker D, et al. Long-acting dihydropyridine calcium antagonists. 4. Synthesis and structure-activity relationships for a series of basic and nonbasic derivatives of 2-[(2-aminoethoxy)methyl]-1,4-dihydropyridine calcium antagonists. J Med Chem. 1990 Feb;33(2):585-91.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Activité biologique
- Description
- IC₅₀ & Target
- In Vivo
Chemical Information
Pureté et documentation
Références

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UK51656

Voir tous les produits spécifiques à Isoform Calcium Channel

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

UK51656 Related Classifications

HY-101707 Related Classifications