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Cat. No.: HY-114255

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Alpha-tocopheryloxyacetic acid

Name: Alpha-tocopheryloxyacetic acid
Brand: MedChemExpress
SKU: HY-114255
Availability: PreOrder

(Synonyms: alpha-TEA)

Alpha-tocopheryloxyacetic acid (alpha-TEA) is an inducer of cancer cell apoptosis pathway. Alpha-tocopheryloxyacetic acid is promising for research of solid and hematological malignancies.

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CAS No.: 261929-52-6
Formule: C₃₁H₅₂O₄
Masse moléculaire:488.74

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (261 KB)

Alpha-tocopheryloxyacetic acid Chemical Structure

CAS No.: 261929-52-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
- Essai clinique
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

Alpha-tocopheryloxyacetic acid (alpha-TEA) is an inducer of cancer cell apoptosis pathway. Alpha-tocopheryloxyacetic acid is promising for research of solid and hematological malignancies^[1]^[2].

Cellular Effect

Cell Line	Type	Value	Description	References
MCF7	EC₅₀	51 μM Compound: alpha-TEA	Induction of apoptosis in human MCF7 cells by AnnexinV/PI/FITC-based flow cytometric analysis Induction of apoptosis in human MCF7 cells by AnnexinV/PI/FITC-based flow cytometric analysis	[PMID: 23092906]
MDA-MB-231	EC₅₀	35 μM Compound: alpha-TEA	Induction of apoptosis in human MDA-MB-231 cells by AnnexinV/PI/FITC-based flow cytometric analysis Induction of apoptosis in human MDA-MB-231 cells by AnnexinV/PI/FITC-based flow cytometric analysis	[PMID: 23092906]

Essai clinique

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

Chemical Information

CAS No. 261929-52-6
Masse moléculaire 488.74
Formule C₃₁H₅₂O₄
SMILES

O=C(O)COC1=C(C)C(C)=C2C(CC[C@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)O2)=C1C
Synonyms

alpha-TEA
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (261 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Gwin W R, et al. A phase I dose-escalation trial of alpha-tocopheryloxyacetic acid and concurrent trastuzumab in patients with treatment refractory HER2+ metastatic breast cancer[J]. 2020.

[2]. Lu N. The anticancer effects of vitamin E derivative alpha-tea in human hematological malignancies[J]. 2010.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

Alpha-tocopheryloxyacetic acid

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Activité biologique
- Description
- Essai clinique
Chemical Information
Pureté et documentation
Références

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Alpha-tocopheryloxyacetic acid

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Alpha-tocopheryloxyacetic acid Related Classifications

HY-114255 Related Classifications

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