AM4299 A
AM4299 A is a thiol protease inhibitor with IC50 values of 73, 390 and 88 nM against Cathepsin B, Cathepsin L and Papain, respectively. AM4299 A shows low toxicity and favorable biosafety in mice. AM4299 A can be used in studies related to osteoporosis and parasitic diseases.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 160825-48-9
- Formule: C15H26N2O6
- Masse moléculaire:330.38
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
Voir tous les produits spécifiques à Isoform Cathepsin
More
Activité biologique
|
Cathepsin C 73 nM (IC50) |
cathepsin L 390 nM (IC50) |
papain 88 nM (IC50) |
AM4299 A specifically inhibits purified bovine spleen cathepsin B (IC50 = 7.3 × 10-8 M), human kidney cathepsin L (IC50 = 3.9 × 10-7 M), and Carica papaya papain (IC50 = 8.8 × 10-8 M), with no activity against bovine pancreas trypsin or α-chymotrypsin at concentrations up to 8.0 × 10-5 M[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 160825-48-9
-
Masse moléculaire 330.38
-
Formule C15H26N2O6
-
SMILES
C(N[C@H](C(NCCCCCO)=O)CC(C)C)(=O)C1C(C(O)=O)O1
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AM4299 A Related Classifications
HY-187615 Related Classifications
Powered by Bioz