ARP

ARP (100 μL; 1 h at 37 °C) detects AP sites and related aldehyde-containing damages in DNA isolated from heat-inactivated, X-irradiated E. coli AB1157 cells, with signal intensity proportional to radiation dose^[1].
ARP (100 μL; 1 h at 37 °C) detects AP sites formed in the DNA of MMS-treated E. coli AB1157 cells. Its signal is proportional to the concentration of MMS and decreases during the repair process after treatment^[1].
ARP (2 mM; 1 h) specifically reacts with apurinic sites in acid-apurinized yeast tRNA^Phe, and its reaction activity is directly proportional to the degree of apurinization^[2].
ARP (0-10 mM; 1 h) specifically binds to abasic sites in chemically synthesized RNA, with a limit of detection of 10 fmoles of abasic sites^[2].
The reactivity of ARP (0-10 mM; 0.5-2 h) with synthetic abasic RNA increases with elevated temperature, prolonged incubation time up to 1 h, acidic pH, and increased ARP concentration^[2].
ARP (2 mM; 1 h) detects apurinic/apyrimidinic sites in in vitro synthesized RNA irradiated with γ-rays in a dose-dependent manner, and this effect occurs at doses ≥5 Gy^[2].
ARP (2 mM; 1 h) detects apurinic/apyrimidinic (AP) sites in in vitro synthesized RNA oxidized by the Fenton reaction in a dose-dependent manner, and covalently binds to abasic glycosyl groups in Fenton reaction-oxidized RNA to form ribose-ARP adducts detectable by LC/MS^[2].
ARP (2 mM; 1 h) detects apurinic/apyrimidinic sites in in vitro synthesized RNA oxidized by peroxynitrite in a dose-dependent manner^[2].
ARP (2 mM; 1 h) detected an increase in the formation of abasic sites in the total RNA of HeLa cells treated with hydrogen peroxide or peroxynitrite^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.