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Cat. No.: HY-159994

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AUPF02

AUPF02, a 5-arylurea uracil derivative, is a potent anti-breast cancer agent, with an IC₅₀ of 23.4 µM for MCF-7 cells.

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CAS No.: 904803-58-3
Formule: C₁₄H₉F₅N₂O
Masse moléculaire:316.23

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

AUPF02 Chemical Structure

CAS No.: 904803-58-3

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

AUPF02, a 5-arylurea uracil derivative, is a potent anti-breast cancer agent, with an IC₅₀ of 23.4 µM for MCF-7 cells^[1].

Chemical Information

CAS No. 904803-58-3
Masse moléculaire 316.23
Formule C₁₄H₉F₅N₂O
SMILES

CC1=CC=C(NC(NC2=C(F)C(F)=C(F)C(F)=C2F)=O)C=C1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocole

All Animals and Diseases

Breast Cancer Modeling
Breast cancer is a heterogeneous cancer, and it has been distinguished into four subtypes: luminal A, luminal B, HER2-positive and basal-like. Molecular mutations, epigenetic alterations, hormone exposure and immune microenvironment are related to the progression of breast cancer.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Sroor FM, et, al. Novel 5-Fluorouracil analogues versus perfluorophenyl ureas as potent anti-breast cancer agents: Design, robust synthesis, in vitro, molecular docking, pharmacokinetics ADMET analysis and dynamic simulations. Bioorg Chem. 2024 Dec:153:107944. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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