AZD1092
AZD1092 is an orally active glucokinase (GK) activator with an EC50 value of 0.03 μM. AZD1092 can be used for the research of Type 2 Diabetes (T2D).
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 871656-65-4
- Formule: C24H26N4O5
- Masse moléculaire:450.49
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
IC50 & Target
EC50: 0.03 μM (glucokinase)[1]
In Vitro
AZD1092 has activity for glucokinase with an EC50 value of 0.03 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Female Zucker rats[1]
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Dosage:1, 3, 10 mg/kg
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Administration:Oral
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Result:Exhibited dose dependent reduction of glucose excursion in oral glucose tolerance tests in high fat fed female Zucker rats and glucose lowering efficacy in free feeding glucose profiles in male Zucker rats.
Chemical Information
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CAS No. 871656-65-4
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Masse moléculaire 450.49
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Formule C24H26N4O5
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SMILES
O=C(C1=CC(O[C@H](CO)C)=CC(OC2=CC=C(C=C2)C(N3CCC3)=O)=C1)NC4=NN(C=C4)C
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AZD1092 Related Classifications
HY-121070 Related Classifications
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