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Camostat

45 Cited Publications
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Based on 45 publication(s) in Google Scholar

Camostat is an orally active trypsin inhibitor. Camostat can reduce pancreatic fibrosis induced by repeated administration of superoxide dismutase inhibitors in rats, and decrease the proliferation and activation of pancreatic stellate cells (PSCs).

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  • Pureté: 99.42%
  • CAS No.: 59721-28-7
  • Formule: C20H22N4O5
  • Masse moléculaire:398.41
  • Stockage:
    Powder   -20°C, 3 years ; In solvent   -80°C, 6 months , -20°C, 1 month
  • Camostat Chemical Structure
    Camostat Chemical Structure
  • Experimental Validation Results for Camostat
  • Experimental Validation Results for Camostat
  • Experimental Validation Results for Camostat
  • Experimental Validation Results for Camostat
  • Experimental Validation Results for Camostat
CAS No.: 59721-28-7
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  • Camostat Chemical Structure
    Camostat Chemical Structure
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    Camostat purchased from MedChemExpress. Usage Cited in: Nat Microbiol. 2025 Nov;10(11):2860-2874. [Abstract]

    Customer Validation
     TMPRSS2 inhibitor Camostat mesylate (66.7 μM; 1 h; 37 ℃) dose-dependently inhibited pseudovirus entry of HKU25 clade or HKU5-1 in Caco-2 cells overexpressing the indicated ACE2s.

  • 1/16

    Camostat purchased from MedChemExpress. Usage Cited in: Nat Microbiol. 2024 Sep;9(9):2383-2394. [Abstract]

    Customer Validation
     TMPRSS2 inhibitor Camostat mesylate (0.01-100 μM) inhibited the WT pseudovirus approximately 3-fold better than the ΔFCS pseudovirus in VeroE6 cells overexpressing hACE2 and TMPRSS2 (VAT cells).

  • 1/16

    Camostat purchased from MedChemExpress. Usage Cited in: Signal Transduct Target Ther. 2022 Mar 11;7(1):83. [Abstract]

    Customer Validation
     Camostat mesylate (2-20 μM; 1 h) inhibited SARS-CoV-2 infection of Caco2 cells in a dose-dependent manner.

  • 1/16

    Camostat purchased from MedChemExpress. Usage Cited in: Nature. 2022 Mar;603(7902):693-699. [Abstract]

    Customer Validation
     VeroE6-TMPRSS2 cells were pretreated with Camostat mesylate (1–50 μM; 2 h) followed by transduction with pseudoviruses carrying the spike protein of SARS-CoV-2 WT, Alpha, Beta, Delta, or Omicron. Pseudovirus entry was quantified by measuring the luciferase signal of the cell lysates at 24 h.p.i.

  • 1/16

    Camostat purchased from MedChemExpress. Usage Cited in: Nature. 2022 Mar;603(7902):693-699. [Abstract]

    Customer Validation
     VeroE6-TMPRSS2 cells were pretreated with Camostat mesylate (1-50 μM; 2 h) and challenged with the indicated authentic SARS-CoV-2 variants at 0.1 m.o.i.. The amount of viral subgenomic envelope RNA in the collected cell lysates at 24 h.p.i. was determined using RT–qPCR.

  • Camostat