Celikalim
Celikalim (Way 120491) is an antihypertensive agent. Celikalim lowers blood pressure through opening potassium channelsin vascular smooth muscle. Celikalim can inhibit white thrombus formation. Celikalim is a potent potassium opener in dog model. Celikalim can be studied in thrombosis-related research.
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- CAS No.: 124916-54-7
- Formule: C20H18F3NO4
- Masse moléculaire:393.36
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
Chemical Information
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CAS No. 124916-54-7
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Masse moléculaire 393.36
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Formule C20H18F3NO4
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SMILES
O=C1N([C@H]2[C@H](O)C(C)(C)OC3=CC=C(OC(F)(F)F)C=C23)CC4=C1C=CC=C4
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Synonyms
Way 120491
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Patelunas-Hoffman, D. M., et al., (1994). Analysis of the potassium channel openers celikalim, pinacidil and cromakalim in platelet models of thrombosis. Thrombosis research, 74(5), 441-452. [Content Brief]
[2]. de Lorenzi F. G. (1994). Celikalim (WAY-120491) increases K+ outward flux in dog and human airway smooth muscle. Pulmonary pharmacology, 7(2), 129-135. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)