ERG-IN-4
ERG-IN-4 (Compound 12) is an orally active, selective ERG inhibitor with an IC50 of 5.2 μM for hERG. ERG-IN-4 activates PXR. ERG-IN-4 exhibits anticancer activity against MTAP-deleted non-small cell lung cancer.
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- CAS No.: 3047672-14-7
- Formule: C24H22F3N7O2
- Masse moléculaire:497.47
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
IC50: 5.2 μM for hERG[1]
Chemical Information
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CAS No. 3047672-14-7
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Masse moléculaire 497.47
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Formule C24H22F3N7O2
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SMILES
CN(N=C1)C2=C1C(N)=NC3=C2C=C(C(N(N(C(C4CC4)=O)C)CC5=NC=C(C(F)(F)F)C=C5)=O)C=C3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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