FJ-5002
FJ-5002 is a telomerase inhibitor with an IC50 of 2 μM. FJ-5002 can induce telomere shortening, increased chromosomal abnormalities, and senescence/crisis-like features in the human leukemia cell line U937. FJ-5002 exhibits antitumor activity and can be used in the study of cancer.
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- CAS No.: 247129-77-7
- Formule: C20H22ClN3OS3
- Masse moléculaire:452.06
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Chemical Information
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CAS No. 247129-77-7
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Masse moléculaire 452.06
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Formule C20H22ClN3OS3
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SMILES
CC1=CSC(/C=C(N(CC)C/2=O)\SC2=C3SC4=CC=CC=C4N\3C)=[N+]1CC.[Cl-]
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Guo WZ, et al. Search for novel anti-tumor agents from ridaifens using JFCR39, a panel of human cancer cell lines. Biol Pharm Bull. 2013;36(6):1008-16. [Content Brief]
[2]. Naasani I, et al FJ5002: a potent telomerase inhibitor identified by exploiting the disease-oriented screening program with COMPARE analysis. Cancer Res. 1999 Aug 15;59(16):4004-11. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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