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Cat. No.: HY-188142

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Gal-PAB

Gal-PAB is a galactose-linker conjugate that can be used for the synthesis of the galactose-modified PROTAC prodrug Gal-ARV-771 (HY-158331). Gal-PAB is applicable to lung cancer research.

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CAS No.: 259684-23-6
Formule: C₂₁H₂₆O₁₁
Masse moléculaire:454.42

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Gal-PAB Chemical Structure

CAS No.: 259684-23-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Gal-PAB is a galactose-linker conjugate that can be used for the synthesis of the galactose-modified PROTAC prodrug Gal-ARV-771 (HY-158331). Gal-PAB is applicable to lung cancer research^[1].

Chemical Information

CAS No. 259684-23-6
Masse moléculaire 454.42
Formule C₂₁H₂₆O₁₁
SMILES

CC(O[C@@H]1[C@H]([C@@H](O[C@@H]([C@@H]1OC(C)=O)COC(C)=O)OC2=CC=C(C=C2)CO)OC(C)=O)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Chang M, et al. Selective Elimination of Senescent Cancer Cells by Galacto-Modified PROTACs. Journal of medicinal chemistry. 2024 May 09;67(9):7301-7311. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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