ZFY - zinc finger protein Y-linked Gene
Also Known as ZNF911
Species: Homo sapiens
About ZFY
This gene has 7 transcripts (splice variants), 74 orthologues and 38 paralogues. Broad expression in testis (RPKM 3.4), prostate (RPKM 3.2) and 20 other tissues.
Summary
This gene encodes a zinc finger-containing protein that may function as a transcription factor. This gene was once a candidate gene for the testis-determining factor (TDF) and was erroneously referred to as TDF. [provided by RefSeq, Jul 2008]
ZFY Products (12)
| mRNA | Protein | Name |
|---|---|---|
| NM_001145275.2 | NP_001138747.1 | zinc finger Y-chromosomal protein isoform 2 |
| NM_001145276.2 | NP_001138748.1 | zinc finger Y-chromosomal protein isoform 3 |
| NM_001369702.1 | NP_001356631.1 | zinc finger Y-chromosomal protein isoform 1 |
| NM_001369703.1 | NP_001356632.1 | zinc finger Y-chromosomal protein isoform 4 |
| NM_001369704.1 | NP_001356633.1 | zinc finger Y-chromosomal protein isoform 4 |
| NM_001369705.1 | NP_001356634.1 | zinc finger Y-chromosomal protein isoform 4 |
| NM_001369706.1 | NP_001356635.1 | zinc finger Y-chromosomal protein isoform 5 |
| NM_001369707.1 | NP_001356636.1 | zinc finger Y-chromosomal protein isoform 5 |
| NM_001369708.1 | NP_001356637.1 | zinc finger Y-chromosomal protein isoform 2 |
| NM_001369709.1 | NP_001356638.1 | zinc finger Y-chromosomal protein isoform 6 |
| NM_001369710.1 | NP_001356639.1 | zinc finger Y-chromosomal protein isoform 7 |
| NM_003411.4 | NP_003402.2 | zinc finger Y-chromosomal protein isoform 1 |
| Molecular Function GO Annotation | Evidence | Références | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
26871637 | GOA |
ZFY Protein Structure
Zfx_Zfy_act: Zfx / Zfy transcription activation region (71 - 406)
zf-C2H2: Zinc finger, C2H2 type (421 - 443)
zf-H2C2_5: C2H2-type zinc-finger domain (452 - 474)
zf-C2H2: Zinc finger, C2H2 type (485 - 506)
zf-H2C2_5: C2H2-type zinc-finger domain (515 - 538)
zf-H2C2_2: Zinc-finger double domain (559 - 580)
zf-H2C2_2: Zinc-finger double domain (586 - 611)
zf-C2H2_4: C2H2-type zinc finger (629 - 652)
zf-C2H2: Zinc finger, C2H2 type (658 - 680)
zf-H2C2_5: C2H2-type zinc-finger domain (686 - 710)
zf-H2C2_2: Zinc-finger double domain (730 - 753)
zf-C2H2: Zinc finger, C2H2 type (772 - 794)
- 0
- 200
- 400
- 600
- 801 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
zinc finger Y-chromosomal protein |
|
ZFY Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | Références |
|---|---|---|---|---|---|---|---|
|
Intra
|
ZFY | P08048 | L3MBTL2 | Homo sapiens | Q969R5 | 32296183 | |
|
Intra
|
ZFY | P08048 | KAT14 | Homo sapiens | Q9H8E8 | 32296183 | |
|
Intra
|
ZFY | P08048 | DMRT3 | Homo sapiens | Q9NQL9 | 32296183 |
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Campomelic Dysplasia |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Nom du produit |
Effect
|
Pureté |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS16054 | ZFY Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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