2. Gene
  3. ZFY - zinc finger protein Y-linked Gene

ZFY - zinc finger protein Y-linked Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as ZNF911

Gene ID: 7544 | Gene type: protein coding

About ZFY

Cytogenetic location: Yp11.2 Genomic coordinates (GRCh38): Y:2,935,381-2,982,506 (from NCBI)

This gene has 7 transcripts (splice variants), 74 orthologues and 38 paralogues. Broad expression in testis (RPKM 3.4), prostate (RPKM 3.2) and 20 other tissues.

Summary

This gene encodes a zinc finger-containing protein that may function as a transcription factor. This gene was once a candidate gene for the testis-determining factor (TDF) and was erroneously referred to as TDF. [provided by RefSeq, Jul 2008]

ZFY Products(12)

mRNA Protein Name
NM_001145275.2 NP_001138747.1 zinc finger Y-chromosomal protein isoform 2
NM_001145276.2 NP_001138748.1 zinc finger Y-chromosomal protein isoform 3
NM_001369702.1 NP_001356631.1 zinc finger Y-chromosomal protein isoform 1
NM_001369703.1 NP_001356632.1 zinc finger Y-chromosomal protein isoform 4
NM_001369704.1 NP_001356633.1 zinc finger Y-chromosomal protein isoform 4
NM_001369705.1 NP_001356634.1 zinc finger Y-chromosomal protein isoform 4
NM_001369706.1 NP_001356635.1 zinc finger Y-chromosomal protein isoform 5
NM_001369707.1 NP_001356636.1 zinc finger Y-chromosomal protein isoform 5
NM_001369708.1 NP_001356637.1 zinc finger Y-chromosomal protein isoform 2
NM_001369709.1 NP_001356638.1 zinc finger Y-chromosomal protein isoform 6
NM_001369710.1 NP_001356639.1 zinc finger Y-chromosomal protein isoform 7
NM_003411.4 NP_003402.2 zinc finger Y-chromosomal protein isoform 1

ZFY Protein Structure

Zfx_Zfy_act

Zfx_Zfy_act: Zfx / Zfy transcription activation region (71 - 406)

zf-C2H2

zf-C2H2: Zinc finger, C2H2 type (421 - 443)

zf-H2C2_5

zf-H2C2_5: C2H2-type zinc-finger domain (452 - 474)

zf-C2H2

zf-C2H2: Zinc finger, C2H2 type (485 - 506)

zf-H2C2_5

zf-H2C2_5: C2H2-type zinc-finger domain (515 - 538)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (559 - 580)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (586 - 611)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (629 - 652)

zf-C2H2

zf-C2H2: Zinc finger, C2H2 type (658 - 680)

zf-H2C2_5

zf-H2C2_5: C2H2-type zinc-finger domain (686 - 710)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (730 - 753)

zf-C2H2

zf-C2H2: Zinc finger, C2H2 type (772 - 794)

  • 0
  • 200
  • 400
  • 600
  • 801 a.a.
Protein Preferred Names Protein Names

zinc finger Y-chromosomal protein

Related Diseases

Diseases Alias
Campomelic Dysplasia

Acampomelic Campomelic Dysplasia

Camptomelic Dysplasia

Campomelic Dysplasia With Autosomal Sex Reversal

Cmpd

CMD1

Cmpd1

Cmpd1/Sra1

Acampomelic Campomelic Dysplasia With Autosomal Sex Reversal

Campomelic Dwarfism

Campomelic Syndrome

Dysplasia, Campomelic

Chronic Myeloproliferative Disorder

Familial Dilated Cardiomyopathy
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS16054 ZFY Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus ZFY MGD MGI:99153