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Gresonitamab

(Synonyms: AMG 910; Anti-Human CD3xClaudin18 2)
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Gresonitamab (AMG 910) is a half-life extended (HLE) bispecific T-cell engager (BiTE) antibody targets CD3-positive T cells and CLDN18.2-expressing tumor cells. Gresonitamab can be used for the research of adenocarcinoma.

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  • Pureté: 99.44%
  • CAS No.: 2413817-97-5
  • Masse moléculaire:106 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Gresonitamab
  • Experimental Validation Results for Gresonitamab
  • Experimental Validation Results for Gresonitamab
  • Gresonitamab Chemical Structure
    Gresonitamab Chemical Structure
CAS No.: 2413817-97-5
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[email protected] [email protected]
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Assay Types
  • 1/16

    (scFv-heavy-kappa)-(scFv-heavy-lambda)-scFc

  • 1/16

    Immobilized Gresonitamab can bind Human CD3 epsilon/CD3e Protein (ECD, His Tag). The EC50 for this effect is 3.97 ng/mL.

  • 1/16

    Flow cytometric analysis of 1×106 Jurkat cells labelling CD3E (red) with Gresonitamab (HY-P99350). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control.

  • Gresonitamab Chemical Structure
    1/16
  • Gresonitamab
  • Immobilized Gresonitamab can bind Human CD3 epsilon/CD3e Protein (ECD, His Tag). The EC50 for this effect is 3.97 ng/mL.
  • Flow cytometric analysis of 1×106 Jurkat cells labelling CD3E (red) with Gresonitamab (HY-P99350). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control.
  • (scFv-heavy-kappa)-(scFv-heavy-lambda)-scFc