GSK223
GSK223 is a quinazolinone NOD1 pathway inhibitor with potential anti-inflammatory activity. GSK223 can selectively inhibit IL-8 release under iE-DAP stimulation without affecting IL-8 secretion caused by TNF receptor, TLR2 or NOD2 agonists. GSK223 does not directly inhibit RIP2 kinase activity.
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- CAS No.: 899758-61-3
- Formule: C21H18FN3O3S2
- Masse moléculaire:443.51
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Chemical Information
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CAS No. 899758-61-3
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Masse moléculaire 443.51
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Formule C21H18FN3O3S2
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SMILES
O=S(C1=CC=C(S1)CC)(NC2=CC(N3C(C)=NC4=C(C3=O)C=CC=C4)=CC=C2F)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)