Indapamide-13C,d3
Indapamide-13C,d3 is 13C and deuterium labeled Indapamide. Indapamide is an orally active sulphonamide diuretic agent, that can reduce blood pressure by decreasing vascular reactivity and peripheral vascular resistance. Indapamide is also can reduce left ventricular hypertrophy.
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- CAS No.: 2934053-07-1
- Formule: C1513CH13D3ClN3O3S
- Masse moléculaire:369.85
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 2934053-07-1
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Unlabeled Cas 26807-65-8
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Masse moléculaire 369.85
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Formule C1513CH13D3ClN3O3S
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SMILES
O=C(C1=CC=C(C(S(=O)(N)=O)=C1)Cl)NN2C3=C(CC2[13C]([2H])([2H])[2H])C=CC=C3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Chaffman, M, et, al. Indapamide. Drugs 28, 189–235 (1984).
[3]. Furman BL, et, al. A further examination of the possible effects of indapamide on glucose tolerance and insulin secretion in the rat and mouse. J Pharm Pharmacol. 1981 Nov;33(11):735-7. [Content Brief]
[4]. Lalande A, et, al. Indapamide, a thiazide-like diuretic, decreases bone resorption in vitro. J Bone Miner Res. 2001 Feb;16(2):361-70. [Content Brief]
[5]. Ma F, et, al. Indapamide lowers blood pressure by increasing production of epoxyeicosatrienoic acids in the kidney. Mol Pharmacol. 2013 Aug;84(2):286-95. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Indapamide-13C,d3 Related Classifications
HY-B0259S1 Related Classifications
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