KU-2285
KU-2285 is an orally active fluorinated 2-nitroimidazole hypoxic cell radiosensitizer. KU-2285 has higher lipophilicity, superior sensitizing activity to Etanidazole (HY-116972), and lower neurotoxicity. KU-2285 can be used in research related to tumor diagnosis.
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- CAS No.: 121077-11-0
- Formule: C8H10F2N4O4
- Masse moléculaire:264.19
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
Chemical Information
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CAS No. 121077-11-0
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Masse moléculaire 264.19
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Formule C8H10F2N4O4
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SMILES
O=C(NCCO)C(F)(F)CN1C=CN=C1[N+]([O-])=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Sasai K, et al. A fluorinated 2-nitroimidazole, KU-2285, as a new hypoxic cell radiosensitizer. Int J Radiat Oncol Biol Phys. 1991 Jun;20(6):1249-54. [Content Brief]
[2]. Shibamoto Y, et al. A phase I study of a hypoxic cell sensitizer KU-2285 in combination with conventional radiotherapy. Radiother Oncol. 1996 Jul;40(1):55-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)