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Cat. No.: HY-161538

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Lenalidomide-C6-Br

Lenalidomide-C6-Br is a conjugate of E3 ligase ligand and linker. Lenalidomide-C6-Br can be utilized for synthesis of PROTAC EGFR degrader 9 (HY-161536).

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CAS No.: 2580970-60-9
Formule: C₂₀H₂₄BrN₃O₄
Masse moléculaire:450.33

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Lenalidomide-C6-Br Chemical Structure

CAS No.: 2580970-60-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Lenalidomide-C6-Br is a conjugate of E3 ligase ligand and linker. Lenalidomide-C6-Br can be utilized for synthesis of PROTAC EGFR degrader 9 (HY-161536)^[1].

Voir tous les produits spécifiques à Isoform E3 Ligase Ligand-Linker Conjugates :

Chemical Information

CAS No. 2580970-60-9
Masse moléculaire 450.33
Formule C₂₀H₂₄BrN₃O₄
SMILES

O=C(CCCCCCBr)NC1=CC=CC2=C1CN(C2=O)C3C(NC(CC3)=O)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Yasheng Zhu, et al. Design, Synthesis, and Biological Evaluation of Novel EGFR PROTACs Targeting C797S Mutation. J Med Chem. 2024 May 9;67(9):7283-7300. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight Molecular Weight

Calculateur de dilution

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Chemical Information
Pureté et documentation
Références

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Lenalidomide-C6-Br

Voir tous les produits spécifiques à Isoform E3 Ligase Ligand-Linker Conjugates